News & Notice

Chung-Ang University is now aiming to become one of the leading education institutions in the world by 2018, its centennial year. It has already set an innovative pace in internationalizing its campus.

  • news
  • notice
  • Campus Life
    • Housing
    • Banking&Post Office
    • Library
    • Other Facilities & Service Centers
    • Activities
    • Useful Information
  • Q&A Board

Current Location : CAU | News & Notice | News

News

News View
Title

Prof. Hyun Seo-gang-led Research Team Publishes Research Result in Prestigious Journal, PNAS

Name 관리자 Date 2018.06.05 Hit 114
Content

현서강 증명사진.jpg이강준 증명사진.jpg

[Prof. Hyun Seo-gang and a student named Lee Gang-jun on the doctoral course of 

CAU’s Department of Life Science]


A research team under the leadership of Prof. Hyun Seo-gang of the Department of Life Science, the College of Natural Sciences, Chung-Ang University (CAU), discovered that nutritional condition of drosophila larvae influences the level of sex hormone activity, and based on this, established a process of changing growth signals. The team’s research result, entitled “Steroid signaling mediates nutritional regulation of juvenile body growth via IGF-binding protein in Drosophila (Prof. Hyun Seo-gang, the corresponding author; a student on the doctoral course named Lee Gang-jun, the first author),” was published in a notable academic journal, Proceedings of the National Academy of Sciences of the United States of America (PNAS), on May 21st, 2018. CAU’s research team successfully formulated a principle from a molecular genetic perspective that nutritional condition during juvenile growth period greatly affects physical growth.


영양상태에 따른 초파리 유충의 성장 조절 기전 모델.png


It was found by the research team that nutritional restriction in third (or later) instar larvae increases levels of the steroid hormone, known as ecdysone, and this activates production of Imaginal morphogenesis protein-Late 2 (Imp-L2), a Drosophila homolog of insulin-like growth factor-binding protein 7 (IGFBP7). This ultimately not only lowers insulin signaling in Drosophila, but also suppresses body growth. The whole mechanism was first revealed by CAU’s research team.


Prof. Hyun-led research team had found the mechanism of how steroid hormone regulates body growth, featured in Genes & Development in 2012. This research, as a follow-up study, laid the foundation for developing a noble treatment and prevention measure of growth disorders, caused by juvenile malnutrition and testosterone-estrogen imbalance.


The College of Natural Sciences’ research laboratory solely led this research project and delivered a fruitful result. This clearly indicates that it has much potential to grow into a research-centered higher institution with world-class research capabilities.

목록
이전글/다음글 보기
이전글 CAU’s Graduate School of International Studies (GSIS) Holds Seoul GSIS Union Language Exchange Program 2018.06.14
다음글 CAU Attends ASEAN University Network & ASEAN+3 Educational Forum 2018.05.29

News List
Number Position Date Hit

End of Content. (Skip Navigation)

Top of the screen